Description
Description: Clexza is a brand name for venetoclax, a targeted therapy used in the treatment of certain types of blood cancers.
Contents: Each tablet contains 100mg of venetoclax.
Uses:
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- Treatment of chronic lymphocytic leukemia (CLL) in adults.
- Treatment of small lymphocytic lymphoma (SLL).
- Used in combination with other medications for acute myeloid leukemia (AML) in patients aged 75 years or older, or those who cannot tolerate intensive chemotherapy.
How it Works: Venetoclax targets and inhibits the BCL-2 protein, which is overexpressed in many cancer cells. By binding to BCL-2, it promotes apoptosis (programmed cell death) in these cells, effectively reducing tumor burden.
Directions for Use: Taken orally once daily with food. A ramp-up dosing schedule is recommended to minimize the risk of tumor lysis syndrome (TLS).
Side Effects:
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- Nausea
- Diarrhea
- Fatigue
- Risk of infections due to low white blood cell counts
- Tumor lysis syndrome (TLS)
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Precautions:
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- Regular monitoring of blood counts is necessary.
- Patients should be monitored for signs of TLS, especially during the initial treatment phase.
- Not recommended during pregnancy or breastfeeding.
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